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Getinge AB ecmo circuit maquet rotaflow i system
Ecmo Circuit Maquet Rotaflow I System, supplied by Getinge AB, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ecmo circuit maquet rotaflow i system/product/Getinge AB
Average 90 stars, based on 1 article reviews
ecmo circuit maquet rotaflow i system - by Bioz Stars, 2026-02
90/100 stars

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Simulated closed loop ECMO circuits primed with fresh whole human blood. (A) Ex vivo ECMO circuit. A reservoir bag containing 30 mL of blood was used to construct a bypass to maintain the pressure of the circuit. A total of 800 mL of fresh whole human blood (<1 h) was used to prime the circuit. (B) In vivo ECMO circuit.

Journal: Frontiers in Medicine

Article Title: Effects of ex vivo Extracorporeal Membrane Oxygenation Circuits on Sequestration of Antimicrobial Agents

doi: 10.3389/fmed.2021.748769

Figure Lengend Snippet: Simulated closed loop ECMO circuits primed with fresh whole human blood. (A) Ex vivo ECMO circuit. A reservoir bag containing 30 mL of blood was used to construct a bypass to maintain the pressure of the circuit. A total of 800 mL of fresh whole human blood (<1 h) was used to prime the circuit. (B) In vivo ECMO circuit.

Article Snippet: Sorin (LivaNova, London, United Kingdom) and Maquet (Getinge AB, Hirrlingen, Germany) ECMO circuits were used to establish self-circulation and were primed with fresh whole human blood.

Techniques: Ex Vivo, Construct, In Vivo

Durg recovery of experimental drugs at different time points in Sorin and Maquet ECMO circuits and corresponding control groups. Average drug recovery vs. time for (A) teicoplanin, (B) tigecycline, (C) micafungin, (D) meropenem, (E) polymyxin B, (F) caspofungin, (G) cefoperazone, (H) sulbactam, and (I) voriconazole in the Maquet (blue) and Sorin (red) circuits and corresponding control groups.

Journal: Frontiers in Medicine

Article Title: Effects of ex vivo Extracorporeal Membrane Oxygenation Circuits on Sequestration of Antimicrobial Agents

doi: 10.3389/fmed.2021.748769

Figure Lengend Snippet: Durg recovery of experimental drugs at different time points in Sorin and Maquet ECMO circuits and corresponding control groups. Average drug recovery vs. time for (A) teicoplanin, (B) tigecycline, (C) micafungin, (D) meropenem, (E) polymyxin B, (F) caspofungin, (G) cefoperazone, (H) sulbactam, and (I) voriconazole in the Maquet (blue) and Sorin (red) circuits and corresponding control groups.

Article Snippet: Sorin (LivaNova, London, United Kingdom) and Maquet (Getinge AB, Hirrlingen, Germany) ECMO circuits were used to establish self-circulation and were primed with fresh whole human blood.

Techniques: Control

Three D’s affecting pharmacokinetics during ECMO.

Journal: BMC Anesthesiology

Article Title: The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenation

doi: 10.1186/1471-2253-13-7

Figure Lengend Snippet: Three D’s affecting pharmacokinetics during ECMO.

Article Snippet: Briefly, Maquet PLS ECMO circuits will be used (Maquet Cardiopulmonary AG, Hechinger Straße, Germany).

Techniques: Drug discovery

Significant sequestration of drugs in the ECMO circuit increases their volumes of distribution leading to suboptimal drug concentrations in the body. A mere increase in administered dose for all drugs during ECMO may not suffice, as the less sequestered drugs may reach toxic levels. A - PVC tubing, B - pump, C - oxygenator (Reproduced with Permission, Shekar et al Journal of Crit Care 2012).

Journal: BMC Anesthesiology

Article Title: The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenation

doi: 10.1186/1471-2253-13-7

Figure Lengend Snippet: Significant sequestration of drugs in the ECMO circuit increases their volumes of distribution leading to suboptimal drug concentrations in the body. A mere increase in administered dose for all drugs during ECMO may not suffice, as the less sequestered drugs may reach toxic levels. A - PVC tubing, B - pump, C - oxygenator (Reproduced with Permission, Shekar et al Journal of Crit Care 2012).

Article Snippet: Briefly, Maquet PLS ECMO circuits will be used (Maquet Cardiopulmonary AG, Hechinger Straße, Germany).

Techniques:

Proposed approach to quantify the PK changes and identify factors underlying these changes to inform the development of guidelines for antibiotic and sedative drug therapy during ECMO. S-SLI-smoke inhalation acute lung injury.

Journal: BMC Anesthesiology

Article Title: The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenation

doi: 10.1186/1471-2253-13-7

Figure Lengend Snippet: Proposed approach to quantify the PK changes and identify factors underlying these changes to inform the development of guidelines for antibiotic and sedative drug therapy during ECMO. S-SLI-smoke inhalation acute lung injury.

Article Snippet: Briefly, Maquet PLS ECMO circuits will be used (Maquet Cardiopulmonary AG, Hechinger Straße, Germany).

Techniques:

Proposed methods to understand the pharmacokinetic changes and optimise drug therapy during extracorporeal membrane oxygenation (ECMO).

Journal: BMC Anesthesiology

Article Title: The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenation

doi: 10.1186/1471-2253-13-7

Figure Lengend Snippet: Proposed methods to understand the pharmacokinetic changes and optimise drug therapy during extracorporeal membrane oxygenation (ECMO).

Article Snippet: Briefly, Maquet PLS ECMO circuits will be used (Maquet Cardiopulmonary AG, Hechinger Straße, Germany).

Techniques: Membrane

Study drugs for which mechanistic and clinical pharmacokinetic (PK) data will be generated

Journal: BMC Anesthesiology

Article Title: The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenation

doi: 10.1186/1471-2253-13-7

Figure Lengend Snippet: Study drugs for which mechanistic and clinical pharmacokinetic (PK) data will be generated

Article Snippet: Briefly, Maquet PLS ECMO circuits will be used (Maquet Cardiopulmonary AG, Hechinger Straße, Germany).

Techniques: Ex Vivo

Ex vivo ECMO circuit model. A -reservoir bladder, B - oxygenator, C - centrifugal pump, D -drug injection and sampling port, E - circuit tubing.

Journal: BMC Anesthesiology

Article Title: The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenation

doi: 10.1186/1471-2253-13-7

Figure Lengend Snippet: Ex vivo ECMO circuit model. A -reservoir bladder, B - oxygenator, C - centrifugal pump, D -drug injection and sampling port, E - circuit tubing.

Article Snippet: Briefly, Maquet PLS ECMO circuits will be used (Maquet Cardiopulmonary AG, Hechinger Straße, Germany).

Techniques: Ex Vivo, Injection, Sampling

Validated ovine ECMO model. Reproduced with permission, Fung et al, ISBT Science Series 2012.

Journal: BMC Anesthesiology

Article Title: The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenation

doi: 10.1186/1471-2253-13-7

Figure Lengend Snippet: Validated ovine ECMO model. Reproduced with permission, Fung et al, ISBT Science Series 2012.

Article Snippet: Briefly, Maquet PLS ECMO circuits will be used (Maquet Cardiopulmonary AG, Hechinger Straße, Germany).

Techniques:

Challenges in drug dosing during extracorporeal membrane oxygenation (ECMO). This critically ill patient received concomitant venovenous ECMO, renal replacement therapy (RRT) and induced hypothermia, all of which can significantly alter pharmacokinetics of vital drugs.

Journal: BMC Anesthesiology

Article Title: The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenation

doi: 10.1186/1471-2253-13-7

Figure Lengend Snippet: Challenges in drug dosing during extracorporeal membrane oxygenation (ECMO). This critically ill patient received concomitant venovenous ECMO, renal replacement therapy (RRT) and induced hypothermia, all of which can significantly alter pharmacokinetics of vital drugs.

Article Snippet: Briefly, Maquet PLS ECMO circuits will be used (Maquet Cardiopulmonary AG, Hechinger Straße, Germany).

Techniques: Membrane, Drug discovery